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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCNX All Species: 16.97
Human Site: S656 Identified Species: 31.11
UniProt: Q96RV3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96RV3 NP_055797.2 2341 258676 S656 H K E R G T D S E H T H K A H
Chimpanzee Pan troglodytes XP_510039 2300 254005 L650 A K T R A R V L S L D S G T V
Rhesus Macaque Macaca mulatta XP_001084081 2342 258864 S657 H K E R G T D S E H T H K A H
Dog Lupus familis XP_537501 2332 257280 T660 A H L G P E G T G K K R T T R
Cat Felis silvestris
Mouse Mus musculus Q9QYC1 2344 258128 S659 H R D R G T D S D H T H R A H
Rat Rattus norvegicus NP_001163818 2343 257924 S658 H K D R G T D S D H T H R A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423893 2312 255194 G653 R V L S L D S G T V A C L N D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923995 2285 252748 P654 G A P A S S R P L T T S K S D
Tiger Blowfish Takifugu rubipres Q98UF7 1703 191329 S98 V E H Q T R E S K G S R G G T
Fruit Fly Dros. melanogaster P18490 3433 367590 S925 D C E Q V S A S S K D Q L L S
Honey Bee Apis mellifera XP_624687 2092 236172 H486 V E T D N K R H Q G A I P K Q
Nematode Worm Caenorhab. elegans NP_492790 1634 183268 A29 P S T S A A A A A S S V T V L
Sea Urchin Strong. purpuratus XP_001195494 2799 311472 I704 A I P K R R A I V E R S T S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 98.7 94.4 N.A. 90.9 91.1 N.A. N.A. 84.9 N.A. 66.7 54.4 29.4 38.7 27.7 35.5
Protein Similarity: 100 98.1 99.4 96.4 N.A. 95.5 95.3 N.A. N.A. 90.8 N.A. 77.7 63 42.9 55.5 41.8 49.2
P-Site Identity: 100 13.3 100 0 N.A. 73.3 80 N.A. N.A. 0 N.A. 13.3 6.6 13.3 0 0 0
P-Site Similarity: 100 13.3 100 6.6 N.A. 100 100 N.A. N.A. 0 N.A. 26.6 40 26.6 13.3 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 0 8 16 8 24 8 8 0 16 0 0 31 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 16 8 0 8 31 0 16 0 16 0 0 0 16 % D
% Glu: 0 16 24 0 0 8 8 0 16 8 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 31 0 8 8 8 16 0 0 16 8 0 % G
% His: 31 8 8 0 0 0 0 8 0 31 0 31 0 0 31 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 8 0 0 0 % I
% Lys: 0 31 0 8 0 8 0 0 8 16 8 0 24 8 0 % K
% Leu: 0 0 16 0 8 0 0 8 8 8 0 0 16 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 8 0 16 0 8 0 0 8 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 16 0 0 0 0 8 0 0 8 0 0 8 % Q
% Arg: 8 8 0 39 8 24 16 0 0 0 8 16 16 0 8 % R
% Ser: 0 8 0 16 8 16 8 47 16 8 16 24 0 16 8 % S
% Thr: 0 0 24 0 8 31 0 8 8 8 39 0 24 16 8 % T
% Val: 16 8 0 0 8 0 8 0 8 8 0 8 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _